62645-46-9

Upstream product

• 1584709-88-5 C₂₆H₃₁ClN₂O₄ 
• 1584709-62-5 (S)-3-(benzyloxy)-1-(4-chlorophenyl)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-one 
• 33342-29-9 5-(4-chlorophenyl)-2-hydroxymethylfuran 
• 1584709-72-7 (S)-3-(benzyloxy)-1-(4-chlorophenyl)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-one 
• 1584709-81-8 C₂₆H₃₁ClN₂O₄ 
• 17221-37-3 2-(4-chlorophenyl)furan 
• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 
• 102732-70-7 <5-(4-Chlorphenyl)-2-furylmethyl>-methyl-(1-methyl-2-phenyl-ethyl)-amin 

Relevant academic research and scientific papers

A defunctionalization concept for the convenient synthesis of bis(5-arylfuran-2-yl)methane scaffolds

The bis(5-arylfuran-2-yl)methane framework has been obtained through defunctionalization of aryl ketones, derived from abundantly available L-(+)-tartaric acid, under the influence of acid. The stereocomponents present in these starting aryl ketones have been found to be insignificant for this transformation. Formation of bis(5-arylfuran-2-yl)methane scaffold 1 has been achieved by using a defunctionalization concept involving aryl ketones 2 under the influence of acid. Ketones 2 are easily accessible from L-(+)-tartaric acid through an umpolung strategy using α-amino nitriles as acyl anion equivalents. The stereocomponent (threo/erythro) present in 2 was not significant for this transformation. Copyright