1584744-74-0Relevant academic research and scientific papers
Asymmetric Catalysis with a Mechanically Point-Chiral Rotaxane
Cakmak, Yusuf,Erbas-Cakmak, Sundus,Leigh, David A.
, p. 1749 - 1751 (2016)
Mechanical point-chirality in a [2]rotaxane is utilized for asymmetric catalysis. Stable enantiomers of the rotaxane result from a bulky group in the middle of the thread preventing a benzylic amide macrocycle shuttling between different sides of a prochi
A switchable [2]rotaxane asymmetric organocatalyst that utilizes an acyclic chiral secondary amine
Blanco, Victor,Leigh, David A.,Marcos, Vanesa,Morales-Serna, José A.,Nussbaumer, Alina L.
supporting information, p. 4905 - 4908 (2014/04/17)
A rotaxane-based switchable asymmetric organocatalyst has been synthesized in which the change of the position of the macrocycle reveals or conceals an acyclic, yet still highly effective, chiral organocatalytic group. This allows control over both the rate and stereochemical outcome of a catalyzed asymmetric Michael addition.
