15850-34-7Relevant academic research and scientific papers
Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists
Van Muijlwijk-Koezen,Timmerman,Vollinga,Frijtag von Drabbe Künzel,De Groote,Visser,IJzerman
, p. 749 - 762 (2007/10/03)
Novel classes of heterocyclic compounds as adenosine antagonists were developed based on a template approach. Structure-affinity relationships revealed insights for extended knowledge of the receptor-ligand interaction. We replaced the bicyclic heterocycl
Substituted 4-Phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A1 receptor
Van Tilburg,Van der Klein,De Groote,Beukers,IJzerman
, p. 2017 - 2019 (2007/10/03)
The synthesis and receptor binding of novel adenosine receptor antagonists is described. We found that non-xanthine 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives may have high affinity and substantial selectivity for the adenosine A1
Synthesis of 2,5-Diarylthiazolo-s-triazoles
Ramachandraiah, G.,Reddy, K. Kondal
, p. 808 - 810 (2007/10/02)
2,5-Diarylthiazolo-s-triazoles (II) have been synthesised via 1-(4-arylthiazol-2-yl)-5-aryltetrazoles (VII).Compounds (VII) have been synthesised by the reaction of 2-aroylamino-4-arylthiazoles (V) with phosphorus pentachloride, and azidolysis of t
