158530-54-2Relevant academic research and scientific papers
Synthesis and diuretic activity of (E)-2-Methyl-6-phenylimidazo[2,1-b]-1,3,4-thiadiazole-5-carboxaldehyde dimethylaminoacetohydrazone
Andreani,Rambaldi,Locatelli,Malandrino,Pifferi
, p. 618 - 619 (2007/10/02)
(E)-2-Methyl-6-phenylimidazo[2,1-b]-1,3,4-thiadiazole-5-carboxaldehyde dimethylaminoacetohydrazone was synthesized and its configuration determined. The diuretic activity of this compound, evaluated in rats in a dosage range of 2.5, 10 and 40 mg/kg, was higher than that of the reference compounds hydrochlorothiazide and furosemide.
