158568-84-4Relevant academic research and scientific papers
Studies on Selective Reductions of Rapamycin
Luengo, Juan I.,Rozamus, Leonard W.,Holt, Dennis A.
, p. 6469 - 6472 (1994)
The reaction of rapamycin (1) with different reductive agents has been studied.As expected, the C14 ketone of the "tricarbonyl" unit is the most electrophilic center in the molecule and could be selectively converted to either the alcohol (Zn/AcOH or DIBA
