1586000-27-2

Upstream product

• 1574334-59-0 (S)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 1574334-36-3 (S)-2-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)-2-hydroxyethyl-4-methylbenzenesulfonate 
• 1586000-23-8 (4R,5S)-2,2-dimethyl-4-[(S)-oxiran-2-yl]-5-vinyl-1, 3-dioxolane 
• 1586000-22-7 (S,E)-5-{(4S,5R)-2,2-dimethyl-5-[(S)-oxiran-2-yl]-1,3-dioxolan-4-yl}pent-4-en-2-ol 
• 1586000-24-9 (S,E)-5-{(4S,5S)-5-[(S)-1-hydroxy-4-(trimethylsilyl)but-3-yn-1-yl]-2, 2-dimethyl-1,3-dioxolan-4-yl}pent-4-en-2-ol 
• 1586000-25-0 (S,E)-5-{(4S,5S)-5-[(S)-1-hydroxybut-3-ynyl]-2,2-dimethyl-1,3-dioxolan-4-yl}pent-4-en-2-ol 
• 1586000-26-1 (S,E)-5-{(4S,5S)-5-[(S)-4-bromo-1-hydroxybut-3-ynyl]-2,2-dimethyl-1,3-dioxolan-4-yl}pent-4-en-2-ol 
• 1586000-21-6 (S,E)-5-{(4S,5S)-5-[(S,E)-1-hydroxy-4-(tributylstannyl)but-3-enyl]-2,2-dimethyl-1, 3-dioxolan-4-yl}pent-4-en-2-ol 
• 1586000-20-5 5-((S,E)-4-hydroxy-4-{(4S,5S)-5-[(S,E)-4-hydroxypent-1-en-1-yl]-2,2-dimethyl-1,3-dioxolan-4-yl}but-1-en-1-yl)-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 23568-31-2 2,3:4,5-di-O-isopropylidene-L-arabinose 
• 22893-94-3 (4R,5S)-4-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-5-vinyl-1,3-dioxolane 

Relevant academic research and scientific papers

Stereoselective total synthesis of cochliomycin A

A convergent and stereoselective synthesis of cochliomycin A, a 14-membered resorcyclic acid lactone, based on chiron approach is described. The key reactions involved olefin cross-metathesis and sodium hydride promoted one-pot intramolecular lactonization. l-Arabinose was used as a chiral pool material for the construction of the key fragment.