15861-67-3

Upstream product

• 15861-66-2 1-methyl-pyrrolizidine 
• 88-89-1 2,4,6-Trinitrophenol 
• 80664-41-1 rel-(1S,7aR)-hexahydro-1-methyl-1H-pyrrolizin-5-one 
• 80664-40-0 rel-(1R,7aR)-hexahydro-1-methyl-1H-pyrrolizin-5-one 
• 17463-81-9 4-Methyl-1-azabicyclo<3.3.0>octane 
• 567-38-4 (±)-pseudoheliotridane 

Relevant academic research and scientific papers

Synthesis of (±)-pseudoheliotridane by allylboration of 1-pyrroline

Reaction of tricrotylborane with 1-pyrroline proceeds stereoselectively to give (1R*, 1′S*)-2-(1-methylallyl)pyrrolidine. The latter was converted to the pyrrolizidine alkaloid (±)-pseudoheliotridane through hydroboration - oxidation - intramolecular cycl

Total syntheses of heliotridane and pseudoheliotridane through nitrodiene–acrylate 6π-electrocyclization/[3+2] cycloaddition

The total syntheses of the pyrrolizidine alkaloids heliotridane and pseudoheliotridane have been accomplished in six steps (overall yields: 24 and 7%, respectively) using, for the first time, the tandem 6π-electrocyclization/[3+2] dipolar cycloaddition of

Hydrogenation of pyrrolizin-3-ones; New routes to pyrrolizidines

Pyrrolizin-3-ones (e.g.1) can be easily hydrogenated to their hexahydro (pyrrolizidin-3-one) derivatives in the presence of heterogeneous catalysts. Good diastereoselectivity (up to >97:3, depending on catalysts and solvent) can be achieved if the pyrroli