158673-96-2

Upstream product

• 65408-91-5 goniothalenol 
• 67-56-1 methanol 
• 1221948-84-0 C₁₄H₁₆O₇S 
• 158673-90-6 Toluene-4-sulfonic acid (S)-2-((S)-2,2-diethyl-[1,3]dioxolan-4-yl)-2-(4-methoxy-benzyloxy)-ethyl ester 
• 158673-94-0 (4S,5S)-5-(4-Methoxy-benzyloxy)-2-phenyl-nona-1,8-dien-4-ol 
• 158673-91-7 (S)-2,2-Diethyl-4-[(S)-1-(4-methoxy-benzyloxy)-pent-4-enyl]-[1,3]dioxolane 
• 158673-92-8 (2S,3S)-3-(4-Methoxy-benzyloxy)-hept-6-ene-1,2-diol 
• 156696-20-7 (2S,3S)-2-(4-methoxybenzyloxy)-3,4-O-(3-pentylidene)-1,3,4-butanetriol 

Downstream Products

• 158673-97-3 (2R,3R,3aR,7aS)-3-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-furo[3,2-b]pyran-5-one 
• 204975-45-1 methyl 3-([2S,3S,4R,5R]-3,4-dihydroxy-5-phenyltetrahydrofuran-2-yl)propionate 
• 158673-98-4 (2R,3R,3aR,7aS)-3-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-2,3,3a,7a-tetrahydro-furo[3,2-b]pyran-5-one 
• 65408-91-5 goniothalenol 

Relevant academic research and scientific papers

Styryl-lactone derivatives and alkaloids from Goniothalamus borneenis (Annonaceae)

Twelve natural products, including two new compounds, goniothalesdiol 1a and goniothalactam 2, were isolated from the bark of the Malaysian tree Goniothalamus borneensis (Annonaceae) and evaluated for their cytotoxic activity. Their structures were elucid

The effect of sulfoxides on the stereoselective construction of tetrahydrofurans: Total synthesis of (+)-goniothalesdiol

Good to excellent stereoselectivities were achieved in the reductive cyclization (with Et3SiH/trimethylsilyl trifluoromethanesulfonate (TMSOTf)) of enantiopure hydroxy sulfinyl ketones en route to 2,5-cis-disubstituted tetrahydrofuran skeletons

Stereoselective ring expansion of vinyl oxiranes: Mechanistic insights and natural product total synthesis

"Chemical Equation Presented" What a (strain) relief! The first broadly applicable, catalytic, and stereoselective vinyl oxirane ring expansion is described (see scheme; hfacac = hexafluoroacetylacetonate). The stereoselectivity was influenced by several reaction parameters, and kinetic studies support a mechanistic proposal involving the in situ formation of a more reactive catalytic species. This ring-expansion reaction has been employed in the asymmetric total synthesis of (+)-goniothalesdiol.

Stereoselective total synthesis of bioactive styryllactones (+)-goniofufurone, (+)7-epi-goniofufurone, (+)-goniopypyrone, (+)-goniotriol, (+)-altholactone, and (-)etharvensin

(Chemical Equation Presented) Stereoselective total synthesis of biologically active styryllactones 7-epi-goniofufurone, goniofufurone, goniopypyrone, goniotriol, altholactone, and etharvensin was achieved in high overall yields from a common intermediate

Synthesis of (+)-goniothalesdiol and (+)-7-epi-goniothalesdiol

A total synthesis of (+)-goniothalesdiol, a 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran isolated from Goniothalamus borneensis (Annonaceae), and its 7-epimer is reported using oxycarbonylation methodology for construction of polyhydroxylated substitut

An enantioselective total synthesis of (+)-altholactone from diethyl L-tartrate

An enantioselective total synthesis of the cis-fused tetrahydrofurano-2-pyrone(+)-altholactone (1) from diethyl L-tartrate via the L-threitol derivative 2 is described. The remaining two stereogenic centers of 1 are introduced by a highly stereoselective