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Upstream product

• 4530-20-5 BOC-glycine 
• 1567373-38-9 2-((t-butoxycarbonyl)(3-(4-chlorophenyl)prop-2-yn-1-yl)amino)acetic acid 
• 158979-29-4 2-((tert-butoxycarbonyl)(prop-2-yn-1-yl)-amino)acetic acid 

Downstream Products

• 1567373-41-4 3-(4-chlorophenyl)-2-(2-ethylphenyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 
• 1567370-84-6 3-(4-chlorophenyl)-2-(2-ethylphenyl)-5-(methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 
• 1567370-93-7 3-(4-chlorophenyl)-2-(2-ethylphenyl)-5-(pyridin-3-ylcarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 
• 1567371-14-5 3-(4-chlorophenyl)-2-(2-ethylphenyl)-5-(furan-2-ylcarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 

Relevant academic research and scientific papers

PYRROLOPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: Formula. (I) wherein R1, R2 R3, Q, and G are defined herein.

Synthesis of substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles by intramolecular nitrilimine cycloaddition

Both substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles have been synthesized by the 3+2 intramolecular dipolar cycloaddition of nitrilimines to alkynes. This cyclization has been extended to more versatile 3-bromo derivatives by the use of alkynylbromides as dipolarophiles.