1586774-30-2Relevant academic research and scientific papers
Privileged phosphine-based metal-organic frameworks for broad-scope asymmetric catalysis
Falkowski, Joseph M.,Sawano, Takahiro,Zhang, Teng,Tsun, Galen,Chen, Yuan,Lockard, Jenny V.,Lin, Wenbin
, p. 5213 - 5216 (2014)
A robust and porous Zr metal-organic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and post-synthetically metalated with Ru and Rh complexes to afford highly enantioselective catalysts for important organic transformations. The Rh-functionalized MOF is not only highly enantioselective (up to >99% ee) but also 3 times as active as the homogeneous control. XAFS studies revealed that the Ru-functionalized MOF contains Ru-BINAP precatalysts with the same coordination environment as the homogeneous Ru complex. The post-synthetically metalated BINAP-MOFs provide a versatile family of single-site solid catalysts for catalyzing a broad scope of asymmetric organic transformations, including addition of aryl and alkyl groups to α,β-unsaturated ketones and hydrogenation of substituted alkene and carbonyl compounds.
