158679-92-6

Upstream product

• 2038-57-5 3-Phenylpropan-1-amine 
• 6404-28-0 Boc-Nle-OH 
• 158679-90-4 methyl 2-((3-phenylpropyl)amino)acetate 

Downstream Products

• 251308-97-1 2-[(S)-2-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-N-((S)-1-{(S)-1-[imino-(2,2,5,7,8-pentamethyl-chroman-6-sulfonylamino)-methyl]-piperidin-3-ylmethyl}-2-oxo-2-thiazol-2-yl-ethyl)-acetamide 
• 251308-69-7 [2-butyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetic acid tert-butyl ester 
• 251308-82-4 [(S)-2-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetic acid 
• 251308-55-1 (S)-3-Butyl-1-(3-phenyl-propyl)-piperazine-2,5-dione 
• 251308-42-6 [((S)-2-Amino-hexanoyl)-(3-phenyl-propyl)-amino]-acetic acid methyl ester 

Relevant academic research and scientific papers

The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1

Utilizing X-ray crystallography and molecular modeling, highly potent and selective peptidomimetic thrombin inhibitors have been designed containing a rigid piperazinedione template. The synthesis and biological activity of these compounds will be described.