158679-90-4Relevant academic research and scientific papers
TERTIARY AMIDES AND METHOD OF USE
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Paragraph 00494; 00495; 00843; 00844, (2017/11/04)
Compunds of Formula (I) and pharmaceutically acceptable salts thereof, wherein G1, G2, G3, L1, L2, and L3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the modulation of lysophosphatidic acid receptor 1. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS
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Paragraph 0104; 0105, (2013/07/25)
The present invent ion provides a compound that can utilize hydrogen isotope and, at the same time, can quantify multiplexed samples at one time, as well as decreasing the cost for synthesis of the labeling agent. In addition, the present invention provid
The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: Part 1
Cody, Wayne L.,Cai, Cuiman,Doherty, Annette M.,Edmunds, Jeremy J.,He, John X.,Narasimhan, Lakshmi S.,Plummer, Janet S.,Rapundalo, Stephen T.,Rubin, J. Ronald,Van Huis, Chad A.,Yves, St-Denis,Winocour, Peter D.,Siddiqui, M. Arshad
, p. 2497 - 2502 (2007/10/03)
Utilizing X-ray crystallography and molecular modeling, highly potent and selective peptidomimetic thrombin inhibitors have been designed containing a rigid piperazinedione template. The synthesis and biological activity of these compounds will be described.
