1587-21-9

Basic information

• Product Name: CITRIC ACID TRI-N-PROPYL ESTER
• Synonyms: TRI-N-PROPYL CITRATE;CITRIC ACID TRI-N-PROPYL ESTER;tripropyl citrate;Citric Acid Tripropyl Ester;2-Hydroxy-1,2,3-propanetricarboxylic acid tripropyl ester;2-hydroxypropane-1,2,3-tricarboxylic acid tripropyl ester;tripropyl 2-hydroxypropane-1,2,3-tricarboxylate
• CAS NO: 1587-21-9
• Molecular Formula: C₁₅H₂₆O₇
• Molecular Weight: 318.36
• EINECS: 216-450-8
• Product Categories: Functional Materials;Hydroxycarboxylic Acid Esters (Plasticizer);Plasticizer
• Mol File: 1587-21-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 198 °C / 13mmHg
• Flash Point: 109oC
• Appearance: /
• Density: 1,08 g/cm3
• Vapor Pressure: 4.36E-06mmHg at 25°C
• Refractive Index: 1.4420-1.4450
• PKA: 11.30±0.29(Predicted)
• CAS DataBase Reference: CITRIC ACID TRI-N-PROPYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CITRIC ACID TRI-N-PROPYL ESTER(1587-21-9)
• EPA Substance Registry System: CITRIC ACID TRI-N-PROPYL ESTER(1587-21-9)

Safety Data

• Hazardous Substances Data: 1587-21-9(Hazardous Substances Data)

Usage

Uses

Used in Plastics and Polymer Industry:
CITRIC ACID TRI-N-PROPYL ESTER is used as a plasticizer for improving the flexibility, durability, and heat and chemical resistance of polyvinyl chloride (PVC) and other polymers. Its incorporation into these materials results in products with enhanced performance characteristics, making them suitable for a wide range of applications.
Used in Food and Beverage Industry:
In the food and beverage sector, CITRIC ACID TRI-N-PROPYL ESTER is used as a flavoring agent and food additive. It imparts a pleasant taste and aroma to products such as beverages, confectionery, and other edible items, enhancing their overall sensory appeal and consumer acceptability.
Used in Pharmaceutical Industry:
CITRIC ACID TRI-N-PROPYL ESTER is utilized in the pharmaceutical industry as a component in the formulation of medications. Its properties allow it to improve the solubility, stability, and bioavailability of active pharmaceutical ingredients, contributing to the effectiveness and safety of various drug formulations.
Used in Cosmetics Industry:
In the cosmetics industry, CITRIC ACID TRI-N-PROPYL ESTER is employed as an emollient and skin conditioning agent in personal care products. Its ability to soften and smooth the skin, as well as its moisturizing effects, make it a valuable ingredient in creams, lotions, and other skincare formulations, promoting healthy and youthful skin appearance.

InChI:InChI=1/C15H26O7/c1-4-7-20-12(16)10-15(19,14(18)22-9-6-3)11-13(17)21-8-5-2/h19H,4-11H2,1-3H3

Upstream product

• 71-23-8 propan-1-ol 
• 77-92-9 citric acid 

Downstream Products

• 10061-74-2 propene-1c,2,3-tricarboxylic acid tripropyl ester 
• 6293-73-8 2-acetoxy-propane-1,2,3-tricarboxylic acid tripropyl ester 

Relevant articles and documents

Robust acidic pseudo-ionic liquid catalyst with self-separation ability for esterification and acetalization

The novel acidic pseudo-ionic liquid catalyst with self-separation ability has been synthesized through the quaternization of triphenylphosphine and the acidification with silicotungstic acid. The pseudo-IL showed high activities for the esterification with average conversions over 90%. The pseudo-IL showed even higher activities for acetalization than traditional sulfuric acid. The homogeneous catalytic process benefited the mass transfer efficiency. The pseudo-IL separated from the reaction mixture automatically after reactions, which was superior to other IL catalysts. The high catalytic activities, easy reusability and high stability were the key properties of the novel catalyst, which hold great potential for green chemical processes.

Preparation method of tripropyl citrate plasticizer

The invention discloses a preparation method of a tripropyl citrate plasticizer. By using citric acid and n-propyl alcohol as raw materials and using macroreticular cation exchange resin as a solid catalyst, the tripropyl citrate plasticizer is synthesized, a water-carrying agent is added in the reaction, and a molar ratio of the citric acid to the n-propyl alcohol is 1:(3.5 to 5.5); mass of the catalyst is 40 to 50 percent of that of the citric acid; mass of the water-carrying agent is 45 to 55 percent of that of the citric acid; the tripropyl citrate plasticizer prepared by adopting the preparation method disclosed by the invention is 99.9 percent in purity and 99.0 percent in yield. The catalyst used by the preparation method can be recycled and repeatedly used; resources are saved; moreover, corrosion to equipment is avoided; a post-treatment process is simple; pollution is reduced; moreover, the excellent product can be obtained; the tripropyl citrate plasticizer can be widely applied to the fields of food, medical treatment, children toys and the like.

Hair growth composition containing citric acid esters

Triesters of citric acid are used for inducing, maintaining or increasing hair growth. Compositions for topical application to mammalian hair or scalp comprise an effective amount of from 1% to 99% by weight of an ester of citric acid having the structure (1): where, R1, R2 and R3 each independently represent a branched or unbranched alkyl, alkenyl, aryl, alkylaryl or arylalkyl group, each said group having from 1 to 18 carbon atoms, R4 represents -H, or a branched or unbranched saturated or unsaturated acyl, alkyl, aryl, alkylaryl or aylalkyl group having from 1 to 18 carbon atoms, in the presence of a cosmetically acceptable vehicle for the citric acid ester and in the absence of solid absorbent for the ester;, said effective amount of said ester being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted, in accordance with the Rat Hair Growth Test.