158705-93-2

Upstream product

• 75-36-5 acetyl chloride 
• 158705-92-1 (1S,2R)-(-)-2-(tert-butyldiphenylsilyloxy)-2-(3,4-dimethoxyphenyl)-phenylethylamine 
• 158705-89-6 (R)-(+)-2-(3,4-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 158666-69-4 (R)-(-)-2-(tert-butyldiphenylsilyloxy)-2-(3,4-di-methoxyphenyl)acetonitrile 

Downstream Products

• 158705-96-5 (1R,3S,4R)-(+)-6,7-dimethoxy-4-hydroxy-1-methyl-3-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 158705-95-4 (3S,4R)-(+)-6,7-dimethoxy-4-hydroxy-1-methyl-3-phenyl-3,4-dihydroisoquinoline 
• 158705-94-3 (3S,4R)-(-)-4-(tert-butyldiphenylsilyloxy)-6,7-dimethoxy-1-methyl-3-phenyl-3,4-dihydroisoquinoline 

Relevant academic research and scientific papers

A Simple Enzymatic Synthesis of (3S,4R)-(+)-4-Hydroxy-3-phenyltetrahydroisoquinolines

An efficient versatile method is presented for the stereospecific synthesis of (+)-4-hydroxy-3-phenyltetrahydroisoquinolines 11 and 12 using (R)-arylcyanohydrins as the chiral starting material.From this asymmetric core, the synthetic process proceeds wit