158732-59-3

Basic information

• Product Name: 2-Propenoic acid,3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-, (2E)-
• Synonyms: 2-Propenoic acid,3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-, (2E)- ;Salvianolic acid F;(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-2-propenoic acid
• CAS NO: 158732-59-3
• Molecular Formula: C17H14O6
• Molecular Weight: 314.28946
• Mol File: 158732-59-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 636.8±55.0 °C(Predicted)
• Appearance: /
• Density: 1.556±0.06 g/cm3(Predicted)
• PKA: 4.55±0.15(Predicted)
• CAS DataBase Reference: 2-Propenoic acid,3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid,3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-, (2E)-(158732-59-3)
• EPA Substance Registry System: 2-Propenoic acid,3-[2-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-, (2E)-(158732-59-3)

Safety Data

• Hazardous Substances Data: 158732-59-3(Hazardous Substances Data)

Usage

Uses

Salvianolic Acid F is found in Danshen, a well-?known traditional Chinese medicine (TCM) used to treat cardiovascular and cerebrovascular diseases.

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Relevant articles and documents

Towards the first synthesis of salvianolic acid F: An unexpected intramolecular Diels-Alder cyclisation

The reaction of tetramethylsalvianolic acid F3 with BBr3 led to the expected salvianolic acid F 2 in 10% yield. 2 underwent Diels-Alder cyclisation to 5 or cyclisation to benzofuran 6 depending on the reaction conditions.

New synthesis method of natural product Salvianolic Acid F

The invention discloses a new synthesis method of a natural product Salvianolic Acid F. The method comprises the following steps: carrying out hydroxyl group protection on 4-methycatechol used as a raw material, carrying out a methyl radical reaction, and

The total synthesis of salvianolic acid F

An expeditious synthesis of salvianolic acid F 2 is described in 10% overall yield. Tetramethyl salvianolic acid F 3 was obtained in six steps in 39% overall yield and was converted into the target molecule using boron tribromide in 26% yield.