158745-56-3Relevant academic research and scientific papers
Synthesis and properties of new 2-alkyl-1,4-benzoxazepine derivatives. Part I. Synthesis and cyclization of 2-phenoxyalkanoic acid derivatives
Kwiecien
, p. 733 - 741 (2007/10/03)
2-Alkyl-1,4-benzoxazepin-3,5-diones (8) were readily prepared by cyclodehydration of 2-(o-carbamoilphenoxy)alkanoic acids (7) in acetic anhydride, and with low yields by the same reaction of 2-(o-carboxyphenoxy)alkanoic acid amides (4). The novel acid amides 4 were synthesized from salicylaldehyde and 2-bromo esters 1, via formyl amides 3. The acid amides 7 were formed directly by condensation of salicylamides with 2-bromo esters 1 in dimethyl formamide or by hydrolysis of esters 6 obtained by the same reaction in methyl-ethyl ketone solution.
Synthesis of 2-Phenoxyhexanal and 2-(o-Formylphenoxy)Hexanoic Acid and Its Derivatives
Kwiecien, H.
, p. 661 - 666 (2007/10/02)
The paper describes the synthesis of 2-phenoxyhexanal and 2-(o-formylphenoxy)hexanoic acid and its derivatives which are intermediate compounds in the synthesis of new heterocyclic compounds.Key words: 2-phenoxyhexanal, 2-phenoxyhexanoic acid derivatives, 2-butylbenzofurane
