1587692-04-3

Basic information

• Product Name: (S,S_S)-N-(tert-butylsulfinyl)-2-nitro-1-phenylethanamine
• Synonyms: (S,S_S)-N-(tert-butylsulfinyl)-2-nitro-1-phenylethanamine
• CAS NO: 1587692-04-3
• Molecular Weight: 270.353
• Mol File: 1587692-04-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S,S_S)-N-(tert-butylsulfinyl)-2-nitro-1-phenylethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S,S_S)-N-(tert-butylsulfinyl)-2-nitro-1-phenylethanamine(1587692-04-3)
• EPA Substance Registry System: (S,S_S)-N-(tert-butylsulfinyl)-2-nitro-1-phenylethanamine(1587692-04-3)

Safety Data

• Hazardous Substances Data: 1587692-04-3(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 862776-58-7 (S)-N-benzylidene-2-methylpropane-2-sulfinamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 1041261-05-5 benzyl N-(2-amino-2-phenylethyl)carbamate 

Relevant articles and documents

ROCK-INHIBITING COMPOUND AND USES THEREOF

Disclosed herein are a compound of formula (I) and a preparation method and uses thereof. The compound shows a good inhibitory activity against ROCK, providing a new medicinal strategy to clinically treat the diseases associated with abnormal ROCK activity.

Base-promoted diastereoselective addition of nitromethane and nitroethane to N-tert-butylsulfinyl imines: Synthesis of N-protected α-amino acids and amino ketones

The reaction of N-tert-butylsulfinyl imines with nitromethane or nitroethane in the presence of NaHCO3 under solvent-free reaction conditions gave β-nitro amine derivatives with reasonable levels of diastereoselectivity. Enantioenriched N-tert-