1587718-60-2Relevant academic research and scientific papers
Regioselectivity-Switchable Intramolecular Hydroarylation of Ynone
Lu, Shiwei,Wu, Feng,Zhu, Shifa
supporting information, p. 5632 - 5638 (2020/12/07)
The switchable catalytic approach to the regioselective intramolecular hydroarylation of ynone has been developed. When ZnI2 was used as catalyst, the umpolung α-arylation of ynone was realized via an addition-elimination process of iodine ion to generate the ortho-phenanthrenequinone methide (o-PQM), which could be trapped by styrene to form benzo[f,h]chromenes through hetero-Diels-Alder reaction. While IPrAuCl/AgSbF6 was applied, however, the β-arylation of ynone took place to afford benzocycloheptene-5-ones in moderate to excellent yields. (Figure presented.).
Synthesis of dibenzocyclohepten-5-ones by electrophilic iodocyclization of 1-([1,1′-Biphenyl]-2-yl)alkynones
Chen, Yu,Huang, Chenlong,Liu, Xiaochen,Perl, Eliyahu,Chen, Zhiwei,Namgung, Jieun,Subramaniam, Gopal,Zhang, Gan,Hersh, William H.
, p. 3452 - 3464 (2014/05/06)
A synthesis of iodo-substituted dibenzocyclohepten-5-ones by the iodine monochloride (or iodine)-induced intramolecular 7-endo-dig cyclization of 1-([1,1′-biphenyl]-2-yl)alkynones is reported. Detailed investigations on the substituent effects during the
