158780-92-8

Upstream product

• 693-02-7 hex-1-yne 
• 4418-14-8 1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-chloro-2(1H)-pyrimidinone 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 

Relevant academic research and scientific papers

Pyrimidine nucleoside compounds and oligonucleoside compounds containing same

Novel 2- and 4-substituted pyrimidine nucleosides and oligonucleosides are provided, as are methods and intermediates useful in preparing same. In preferred embodiments, one of the 2- and 4-substituents is =O, =NH, or =NH2+ and the other is Q, =C (RA)-Q,

Synthesis of C-4 substituted pyrimidine nucleoside analogs. Preparation of several 4-(2-oxoalkylidene)-2(1H)-pyrimidinone ribonucleosides

A series of 4-(1-alkynyl)-2(1H)-pyrimidinone ribonucleosides were synthesized from the Pd-catalyzed coupling of terminal alkynes to the 4-chloropyrimidin-2-one ribonucleoside (2). These compounds were hydrated, using three different methods, to afford the