4418-14-8

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 158780-91-7 4-chloro-2-(2-trimethylsilanyl-ethoxy)-pyrimidine 
• 14215-97-5 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose 

Downstream Products

• 158780-92-8 4-(1-hexynyl)-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 158781-04-5 4-(2-thiohexenyl)-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 18354-06-8 arabinosyluracil-5'-monophosphate 
• 2797-17-3 2',3'-O-isopropylidene-5-fluorouridine 
• 58-96-8 uridine 
• 362-43-6 2',3'-O-isopropylideneuridine 
• 3083-77-0 araU 
• 3736-77-4 2,2'-Anhydrouridine 
• 158781-00-1 4-(methyl 2-oxohexenoate)-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 158780-97-3 4-(2-oxohexenyl)-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 158780-96-2 4-ethynyl-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone 
• 1748-04-5 tribenzoyl uridine 
• 90289-28-4 diethyl 1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone-4-phosphonate 
• 95305-84-3 benzyl N-(1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)pyrimidin-2(1H)-on-4-yl)glycinate 

Relevant academic research and scientific papers

Pyrimidine nucleoside compounds and oligonucleoside compounds containing same

Novel 2- and 4-substituted pyrimidine nucleosides and oligonucleosides are provided, as are methods and intermediates useful in preparing same. In preferred embodiments, one of the 2- and 4-substituents is =O, =NH, or =NH2+ and the other is Q, =C (RA)-Q,

Synthesis of C-4 substituted pyrimidine nucleoside analogs. Preparation of several 4-(2-oxoalkylidene)-2(1H)-pyrimidinone ribonucleosides

A series of 4-(1-alkynyl)-2(1H)-pyrimidinone ribonucleosides were synthesized from the Pd-catalyzed coupling of terminal alkynes to the 4-chloropyrimidin-2-one ribonucleoside (2). These compounds were hydrated, using three different methods, to afford the