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N-[2,2,2-trifluoro-1-methylethylidene]aniline, also known as 2,2,2-trifluoro-N-(phenylmethylene)acetamide, is an organic compound with the chemical formula C9H8F3NO. It is a colorless to pale yellow liquid with a molecular weight of 201.16 g/mol. N-[2,2,2-trifluoro-1-methylethylidene]aniline is characterized by the presence of a trifluoromethyl group (CF3) attached to a methylene group (CH2), which is in turn connected to an aniline moiety (C6H5NH2). The trifluoromethyl group imparts unique chemical and physical properties to the molecule, such as increased lipophilicity and stability. N-[2,2,2-trifluoro-1-methylethylidene]aniline is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those containing the trifluoromethyl group. Due to its reactivity and potential toxicity, it is essential to handle N-[2,2,2-trifluoro-1-methylethylidene]aniline with proper safety precautions and in accordance with relevant regulations.

1588-37-0

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1588-37-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1588-37-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,8 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1588-37:
(6*1)+(5*5)+(4*8)+(3*8)+(2*3)+(1*7)=100
100 % 10 = 0
So 1588-37-0 is a valid CAS Registry Number.

1588-37-0Relevant academic research and scientific papers

A physico-chemical investigation of fluorine-enriched quinolines

Aribi, Fallia,Panossian, Armen,Jacquemin, Denis,Vors, Jean-Pierre,Pazenok, Sergii,Leroux, Frédéric R.,Elhabiri, Mourad

, p. 10036 - 10047 (2018/06/18)

Quinoline derivatives bearing fluoroalkyl groups at both 2 and 4 positions are scarcely described in the literature. Nevertheless, the addition of fluorine onto the quinoline core might bring about new interesting physico-chemical properties. To confirm t

PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES

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Page/Page column 7, (2017/08/23)

The invention relates to a novel process for preparing polyfluoroalkylated quinolines from ketimines in the presence of fluoroalkylamino reagents.

Aza-Henry Reaction with CF3-Ketimines: An Efficient Approach to Trifluoromethylated β-Nitroamines, 1,2-Diamines, α-Aminooximes, and Imidazolidinones

Kutovaya, Irina V.,Shmatova, Olga I.,Tkachuk, Viktor M.,Melnichenko, Nina V.,Vovk, Mikhail V.,Nenajdenko, Valentine G.

, p. 6749 - 6761 (2015/10/29)

CF3-Substituted ketimines synthesized from trifluoroacetone, hexafluoroacetone, and trifluoroacetophenones were studied in aza-Henry reactions with nitroalkanes. We found that nitromethane and nitropropane react with CF3-substituted

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