158830-50-3

Basic information

• Product Name: Δ6,7-Baccatin III
• Synonyms: Δ6,7-Baccatin III;(2aR,4aR,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-1,2a,4a,6,9,10,11,12,12a,12b-decahydro-9,11-dihydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
• CAS NO: 158830-50-3
• Molecular Formula: C₃₁H₃₆O₁₀
• Molecular Weight: 568.61154
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 158830-50-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 676.959 °C at 760 mmHg
• Flash Point: 215.01 °C
• Appearance: Off-white solid
• Density: 1.358 g/cm³
• Storage Temp.: -20?C Freezer
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: Δ6,7-Baccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: Δ6,7-Baccatin III(158830-50-3)
• EPA Substance Registry System: Δ6,7-Baccatin III(158830-50-3)

Safety Data

• Hazardous Substances Data: 158830-50-3(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Δ6,7-Baccatin III is an intermediate used in the preparation of Pacitaxel derivatives.

Upstream product

• 158811-19-9 10-acetyl-7-trifluoromethanesulfonate baccatin III 
• 27548-93-2 baccatin III 
• 115437-21-3 7-(triethylsilyl)baccatin III 
• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 
• 32981-86-5 10-deacetylbaccatin III 

Downstream Products

• 172666-21-6 C₄₈H₄₈F₃NO₁₆S 
• 172666-20-5 C₄₇H₄₉NO₁₄ 
• 172666-19-2 C₄₇H₄₇NO₁₂ 

Relevant articles and documents

Fluorinated taxane compound, preparation method therefor and application of fluorinated taxane compound

The invention discloses a fluorinated taxane compound, a preparation method therefor and an application of the fluorinated taxane compound. The compound has a structural general formula represented bya formula I. Proven by pharmacological experiments, compared with paclitaxel, a series of fluorinated taxane derivatives synthesized by the method have cytotoxicity superior to that of the paclitaxelto a multidrug-resistant human mammary cancer cell line MCF-7/Adr and an ovarian cancer cell line NCI/Adr and represent cytotoxicity superior to that of the paclitaxel to a colon cancer cell line HCT-116 with overexpressed neoplasm stem cells.