158830-50-3 Usage
Uses
Used in Pharmaceutical Industry:
Δ6,7-Baccatin III is used as a key intermediate for the production of Paclitaxel derivatives, which are chemotherapeutic agents. These derivatives are crucial in the treatment of various types of cancer due to their ability to disrupt cancer cell division and growth.
Used in Anticancer Applications:
Δ6,7-Baccatin III is used as a precursor in the synthesis of anticancer drugs, specifically Paclitaxel and its analogs. These drugs are effective against a range of cancers, including breast, ovarian, and lung cancer, among others. The compound contributes to the development of more potent and targeted cancer therapies by enabling the production of more effective Paclitaxel derivatives.
Used in Drug Development:
Δ6,7-Baccatin III is utilized as a starting material for the development of novel anticancer drugs. Its unique chemical properties make it a valuable component in the creation of new pharmaceutical compounds with improved efficacy, reduced side effects, and enhanced patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 158830-50-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,8,3 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 158830-50:
(8*1)+(7*5)+(6*8)+(5*8)+(4*3)+(3*0)+(2*5)+(1*0)=153
153 % 10 = 3
So 158830-50-3 is a valid CAS Registry Number.
158830-50-3Relevant academic research and scientific papers
Fluorinated taxane compound, preparation method therefor and application of fluorinated taxane compound
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Paragraph 0048; 0085; 0099-0101, (2019/08/30)
The invention discloses a fluorinated taxane compound, a preparation method therefor and an application of the fluorinated taxane compound. The compound has a structural general formula represented bya formula I. Proven by pharmacological experiments, compared with paclitaxel, a series of fluorinated taxane derivatives synthesized by the method have cytotoxicity superior to that of the paclitaxelto a multidrug-resistant human mammary cancer cell line MCF-7/Adr and an ovarian cancer cell line NCI/Adr and represent cytotoxicity superior to that of the paclitaxel to a colon cancer cell line HCT-116 with overexpressed neoplasm stem cells.
Process for the preparation of 4, 10 beta- diacetoxy-2 alpha-benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19-norcyclopropa [g] tax-11-ene
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Page 3, (2008/06/13)
There is disclosed a process for the preparation of 4 -acetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9 -oxo-19-norcyclopropa[g] tax-11-ene from 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-7β-(trifluoromethyl sulfonyloxy) tax-11-ene by re
