158867-57-3

Upstream product

• 101294-01-3 4-methyl-N-(3-oxo-3-phenyl-propyl)benzenesulfonamide 
• 38455-36-6 N-tosyl-2-phenylazetidine 

Downstream Products

• 158867-59-5 2-(trimethylsilyl)ethyl N-(3-hydroxy-3-phenylpropyl)-N-tosylglycinate 
• 158867-55-1 (2R,4aS,5aS,8R,9aR,9bR)-1-perhydro-2,8-diphenyl-2H,5H,8H-bis<1,3>dioxino<5,4-b:4',5'-d>pyrrolidine 
• 158867-56-2 dimethyl (2S,5S)-1-pyrrolidine-2,5-dicarboxylate 
• 158867-60-8 2-(trimethylsilyl)ethyl N-(2-benzoylethyl)-N-tosylglycinate 
• 158867-54-0 (2S,5S)-1--2,5-dimethylpyrrolidine 
• 158867-61-9 N-(2-benzoylethyl)-N-tosylglycine 

Relevant academic research and scientific papers

Lewis acid mediated SN2-type nucleophilic ring opening followed by [4+2] cycloaddition of N-tosylazetidines with aldehydes and ketones: synthesis of chiral 1,3-oxazinanes and 1,3-amino alcohols

A highly efficient strategy for Cu(OTf)2 mediated SN2-type nucleophilic ring opening followed by [4+2] cycloaddition reactions of enantiopure 2-phenyl-N-tosylazetidines with various aldehydes and ketones afforded a variety of substit

Asymmetric synthesis of 3-hydroxyprolines by photocyclization of N-(2-benzoylethyl)glycinamides

The chiral N-(2-benzoylethyl)-N-tosylglycinamides 1a-c were prepared from the C2-symmetric pyrrolidines 5a-c. Irradiation of these ketones 1a-c gave cis-3-hydroxyprolinamides 10-12 in moderate to good yields (Scheme 3). The de of the photocycli