1588972-64-8

Basic information

• Product Name: 1-(2-((4-chlorophenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one
• Synonyms: 1-(2-((4-chlorophenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one
• CAS NO: 1588972-64-8
• Molecular Weight: 322.791
• Mol File: 1588972-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-((4-chlorophenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-((4-chlorophenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one(1588972-64-8)
• EPA Substance Registry System: 1-(2-((4-chlorophenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one(1588972-64-8)

Safety Data

• Hazardous Substances Data: 1588972-64-8(Hazardous Substances Data)

Upstream product

• 873-73-4 4-n-chlorophenylacetylene 
• 26260-02-6 2-iodobenzaldehyde 
• 1251832-81-1 2-[(4-chlorophenyl)ethynyl]benzaldehyde 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 1588973-14-1 C₂₀H₁₇ClO₂ 

Downstream Products

• 1588971-91-8 3'-(4-chlorophenyl)-3,4,4'-triiodo-5,5-dimethyl-5H-spiro[furan-2,1'-isochromene] 
• 1588971-93-0 (E)-3'-((4-chlorophenyl)iodomethylene)-3,4-diiodo-5,5-dimethyl-3'H,5H-spiro[furan-2,1'-isobenzofuran] 

Relevant articles and documents

Facile synthesis of halogenated spiroketals via a tandem iodocyclization

A strategy for the synthesis of spiroketal compounds through a tandem iodocyclization of 1-(2-ethynylphenyl)-4-hydroxybut-2-yn-1-one derivatives is presented. This reaction could proceed under very mild conditions in a short time and avoid the use of expensive and toxic metal catalysts. Moreover, the resulting halides can be further exploited by subsequent palladium-catalyzed coupling reactions, which act as the important intermediates for building other valuable compounds.