1589-01-1Relevant academic research and scientific papers
Friedlaender synthesis of polysubstituted quinolines and naphthyridines promoted by propylphosphonic anhydride (T3P) under mild conditions
Jida, Mouhamad,Deprez, Benoit
supporting information; experimental part, p. 869 - 873 (2012/07/03)
A new convenient, efficient and environmentally eco-friendly protocol for Friedlaender synthesis of polysubstituted quinolines and naphthyridines is described. A wide variety of new products were readily prepared in the presence of propylphosphonic anhydride (T3P) in short reaction times and excellent yields under mild conditions. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2012.
Microwave assisted friedlander condensation catalyzed by clay
Sabitha, Gowravaram,Satheesh Babu,Subba Reddy,Yadav
, p. 4403 - 4408 (2007/10/03)
Clay catalyzed Friedlander condensation of 2-amino arylaldehyde or ketone with carbonyl compounds containing α-methylene group has been achieved in solvent free condition under microwave irradiation to give polycyclic quinoline derivatives.
