15892-09-8

Upstream product

• 373-02-4 nickel diacetate 
• 1263-63-4 mesoporphyrin IX DME 
• 15304-70-8 {dimethyl-7,12-divinyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionato^(2-)}nickel(II) 
• 5522-66-7 protoporphyrin IX dimethyl ester 

Relevant academic research and scientific papers

A convenient hydrogenation method for the synthesis of metallo- mesoporphyrin IX dimethyl esters via self-catalyzed CoCl2-NaBh 4 reagent system

A convenient protocol has been developed for the hydrogenation of metallo-protoporphyrin IX dimethyl esters (MPPDMEs) to their mesoporphyrin analogues using CoCl2-NaBH4 reagent system. Metallo-porphyrin complexes were found to perform as self-catalysts in this procedure. This method provides several advantages such as safe and simple procedure, short reaction time, high yields and low cost. Copyright

METHOD OF PREPARING PORPHYRIN DERIVATIVES, PORPHYRIN DERIVATIVES, USES THEREOF AND PHARMACEUTICAL COMPOSITIONS

Method of preparing a porphyrin derivative starting from a meso-substituted porphyrin compound. According to the invention, the meso-substituted porphyrin compound used is a meso-(2'-cyanovinyl)-substituted porphyrin compound, wherein said meso-(2'-cyanovinyl)-substituted porphyrin compound, in a form in which its porphyrin ring is complexed with a bivalent metal ion is converted, in the presente of an acid for which 0 pKa 5 and an oxidising agent; or in the presence of a Vilsmeier reagent, into a porphyrin derivative having a quinoline-ring system ring peri-condensed to the porphyrin ring.

The influence of the nature of the solvent and the porphyrin on the mechanism of the formation of metalloporphyrins

Characteristic features of the kinetics of formation of certain d-metal complexes of chlorophyll-group porphyrins - pyrroporphyrin, phylloporphyrin, rhodoporphyrin, and mesoporphyrin - were investigated in a series of coordinating solvents a in the temperature range 288 - 308 K.Additional considerations as regards the mechanism of the formation of the metalloporphyrins are adduced.

Does one-electron transfer to nickel(II) porphyrins involve the metal or the porphyrin ligand?

Nickel( I ) complexes can be reversibly produced by one-electron electrochemical reduction of nickel(II) porphyrins within the time scale of cyclic voltammetry as well as thin-layer and conventional cell electrolysis in solvents such as dimethylformamide and benzonitrile. UV-vis and ESR spectroscopies indicate the formation of a nickel(I) complex rather than the anion radical of the nickel(II) porphyrin. ESR data suggest an out-of-plane displacement of the nickel(I) ion caused by the insufficient size of the hole offered by the porphyrin ligand.