1589534-70-2Relevant academic research and scientific papers
Synthesis of benzofuro[2,3-c]pyridines via a one-pot three-component reaction
Hu, Jiaxing,Deng, Zhihong,Zhang, Xueqiong,Zhang, Fanglin,Zheng, Hua
supporting information, p. 4885 - 4889 (2014/07/07)
A convenient one-pot reaction was conducted by mixing bromoacetophenone, a functionalized α,β-unsaturated ketone and potassium hydroxide in tetrahydrofuran at room temperature, ammonium acetate was added and heated to reflux, resulting in four chemical bonds forming from easily accessible substrates. This process provides a flexible and rapid synthetic route for the construction of polysubstituted benzofuro[2,3-c]pyridines in moderate to good yields. This journal is the Partner Organisations 2014.
Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions
Rao, Yin,Li, Zhexian,Yin, Guodong
, p. 2213 - 2218 (2014/04/17)
A clean and efficient method for the domino synthesis of new functionalized benzofuro[2,3-c]pyridines from easily accessible 2-hydroxychalcones, α-bromo ketones and ammonium acetate is described. Furan and pyridine ring moieties are ingeniously formed in
