158979-56-7Relevant academic research and scientific papers
Carbon-carbon bond formation in regio- and stereoselective palladium-catalyzed cyclization of allene-substituted conjugated dienes
Loefstedt, Joakim,Franzen, Johan,Baeckvall, Jan-E.
, p. 8015 - 8025 (2007/10/03)
Regio- and stereoselective palladium-catalyzed reactions of allene-substituted 1,3-dienes 1 in acetic acid at room temperature lead to cyclization with formation of a carbon-carbon bond between the middle carbon of the allene and the terminal carbon of the 1,3-diene. Two different types of reactions, both that constitute 1,4-carboacetoxylations of the 1,3-diene, have been developed. In one of the reactions, Pd(II) catalyzes the oxidation of 1 to bicyclic compounds 2, and in the other, Pd(0) catalyzes the transformation of 1 to bicyclic compounds 3. The products 2 are useful for further synthetic tr0nsformations and undergo Diels-Alder reactions with dienophiles to give polycyclic ring systems.
Carbon-carbon bond formation in palladium(II)-catalyzed intramolecular 1,4-oxidation of conjugated dienes
Baeckvall, Jan-E.,Nilsson, Ylva I. M.,Andersson, Pher G.,Gatti, Roberto G. P.,Wu, Jinchang
, p. 5713 - 5716 (2007/10/02)
Palladium(II)-catalyzed 1,4-oxidation of conjugated dienes involving a carbocyclization has been developed. Chloropalladation of the triple bond in a dienyne and subsequent addition of the vinylpalladium to the conjugated diene creates a (π-allyl)palladiu
