1590400-89-7Relevant articles and documents
Palladium-catalyzed glycosylation: Novel synthetic approach to diverse n -heterocyclic glycosides
Ji, Li,Xiang, Shao-Hua,Leng, Wei-Lin,Le Mai Hoang, Kim,Liu, Xue-Wei
supporting information, p. 1357 - 1360 (2015/03/30)
An efficient and highly stereoselective method for the construction of N-heterocyclic glycosides is reported. This method is based on a palladium-catalyzed allylation which proceeded to provide N-heterocyclic glycosyl compounds in good-to-excellent yields with β- or α-selectivity. Various N-nucleophiles were examined for this reaction and selected N-glycosyl isatin substrates were further elaborated to bis-indole sugars which have potential as antiproliferative drugs.