159099-24-8

Basic information

• Product Name: 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-xylofuranose
• Synonyms: 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-xylofuranose
• CAS NO: 159099-24-8
• Molecular Weight: 340.305
• Mol File: 159099-24-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-xylofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-xylofuranose(159099-24-8)
• EPA Substance Registry System: 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-xylofuranose(159099-24-8)

Safety Data

• Hazardous Substances Data: 159099-24-8(Hazardous Substances Data)

Usage

Chemical class

Carbohydrates

Parent compound

D-xylofuranose

Structural modification

Five-membered ring sugar molecule with acetyl and benzoyl groups attached to hydroxyl functional groups and a fluorine atom at the 3-position

Potential applications

Organic chemistry and drug development

Structural modifications

Can alter properties and biological activities

Usage

Building block in the synthesis of more complex molecules

Upstream product

• 18530-81-9 (R)-1-((3aR,5R,6S,6aS)-6-fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol 
• 14686-89-6 (1,2:5,6)-di-O-isopropylidene-D-gulose 
• 14049-05-9 3-deoxy-1,2;5,6-di-O-isopropylidene-3-fluoro-α-D-glucofuranose 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 620630-82-2 1,2 5,6-O-di(isopropylidene)-α-D-allofuranose 
• 70722-99-5 (3aR,5R,6S,6aS)-6-fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carbaldehyde 
• 108-24-7 acetic anhydride 
• 125291-12-5 ((3aR,5R,6S,6aS)-6-fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 18530-84-2 3-deoxy-3-fluoro-1,2-O-isopropylidene-α-D-xylofuranose 
• 532-20-7 D-xylofuranose 
• 6698-46-0 5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranos-3-ulose 
• 6612-91-5 ((3aR,5R,65,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 37077-81-9 1,2-isopropylidene-α-D-ribofuranose 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 

Downstream Products

• 158980-88-2 1-(2-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-β-D-xylofuranosyl)thymine 
• 125291-17-0 9-(2,3-dideoxy-3-fluoro-β-D-xylofuranosyl)guanine 
• 125291-15-8 9-(3-deoxy-3-fluoro-β-D-xylofuranosyl)guanine 
• 125291-16-9 N2-acetyl-9-(5-O-benzoyl-2,3-dideoxy-3-fluoro-β-D-xylofuranosyl)guanine 
• 917110-29-3 3'-deoxy-3'-fluoro-5-methyl-1-β-D-xylofuranosyluracil 
• 917110-29-3 1-(3-deoxy-3-fluoro-β-D-lyxofuranosyl)thymine 
• 158980-89-3 N³-benzoyl-1-(2-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-β-D-xylofuranosyl)thymine 

Relevant articles and documents

Phosphoramidate derivatives of nucleoside compounds and uses of derivatives

The invention belongs to the technical field of medicines, and relates to phosphoramidate derivatives of nucleoside compounds, uses of the phosphoramidate derivatives, and a pharmaceutical compositioncontaining the compounds. The derivatives and pharmaceu

Synthesis of a 2,3-dideoxy-2,3-difluorofuranose with the D-lyxo configuration. An intramolecular rearrangement of methyl 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-D-lyxofuranoside observed during the attempted synthesis of 1-(2,3-dideoxy-2,3-difluoro-β-D-lyxof

A new sugar, methyl 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-D-lyxofuranoside (8), which features fluorine substituents on adjacent carbon positions above the plane of the tetrahydrofuran ring, was synthesized from 1,2:5,6-di-O-isopropylidene-α-D-allofuranose

SYNTHESIS OF 9-(3-DEOXY- AND 2,3-DIDEOXY-3-FLUORO-β-D-XYLOFURANOSYL)GUANINES AS POTENTIAL ANTIVIRAL AGENTS

The first synthesis of the title compounds 8 and 10 was accomplished by a multi-step approach involving prior preparation of a suitably protected fluorosugar 6.