15911-93-0

Usage

Uses

Used in Chemical Research:
2,4,6-Tris(prop-2-yn-1-yloxy)-1,3,5-triazine is used as a research compound for its unique molecular structure, which allows for various chemical reactions. Its potential applications in the field of chemistry are being explored, particularly in the synthesis of new compounds and materials.
Used in Laboratory Settings:
2,4,6-Tris(prop-2-yn-1-yloxy)-1,3,5-triazine is used as a laboratory reagent for conducting experiments and testing its reactivity with other substances. Its properties and behavior in different conditions are of interest to researchers, who may use it to develop new chemical processes or understand its interactions with other compounds.
Used in Material Science:
2,4,6-Tris(prop-2-yn-1-yloxy)-1,3,5-triazine is used as a precursor in the development of new materials with specific properties. Its unique structure may contribute to the creation of advanced materials with applications in various industries, such as electronics, pharmaceuticals, or environmental protection.

InChI:InChI=1/C12H9N3O3/c1-4-7-16-10-13-11(17-8-5-2)15-12(14-10)18-9-6-3/h1-3H,7-9H2

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 107-19-7 propargyl alcohol 

Downstream Products

• 632330-00-8 C₃₃H₃₀N₁₂O₃ 
• 1393596-52-5 C₁₀₂H₉₆N₁₈O₂₄ 
• 108-80-5 isocyanuric acid 

Relevant academic research and scientific papers

Design of novel photosensitizers and controlled singlet oxygen generation for photodynamic therapy

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability to produce singlet oxygen. In this work, iodinated or brominated boron dipyrromethene-bearing trimers (5and6) were prepared as photosensitizers and their molecular structures were characterized by mass spectrometry and NMR (1H and13C) spectroscopy. Their photophysical and photochemical abilities were also evaluated in detail. The molar absorption coefficient (ε) of compound5was found to be 2.5 times higher than that of compound6. The photosensitizer (5), bearing iodinated BODIPY units, exhibited almost a non-fluorescent profile with a fluorescence lifetime of 0.12 ns, whereas the other photosensitizer (6) exhibited a more moderate fluorescence character with a fluorescence lifetime of 1.22 ns. The singlet oxygen quantum yields of the photosensitizers were determined to be 0.88 and 0.76, respectively, by the chemical trapping method. Moreover, the biological assessment of the novel compounds showed that these PSs were internalized into the cells and triggered cell death in a light source-dependent manner, underlying the success of the compounds in PDTin vitro.

Synthesis of podands with cyanurate or isocyanurate cores and terminal triple bonds

The synthesis of podands with cyanuric or isocyanuric acid cores and oligoethyleneoxy pendant arms exhibiting terminal triple bonds or brominated triple bonds is reported. The starting material for cyanuric acid derived podands is commercially available c

Novel Bodipy- triazine conjugates: Synthesis and the generation of singlet oxygen

Novel Bodipy decorated triazine conjugates were successfully designed and synthesized by the click reaction of azido functionalized di-styryl Bodipys with propargyl alkoxide substituted triazine. The identities of newly synthesized compounds were confirmed by using 1H and 13C NMR spectroscopies. The molecular structure of propargyl alkoxide substituted triazine was also determined by X-ray crystallography. The photophysical (fluorescence lifetime and fluorescence quantum yield) and photochemical (the singlet oxygen generation capabilities and appropriate photo degradation by light irradiation) properties of Bodipy- triazine conjugates were investigated for determination of their fluorescence and photosensitizer abilities. These results will provide further insight and motivation for development of Bodipy based singlet oxygen photosensitizer systems.

Heterogeneous Organocatalysts Based on a Triazine-Triazole Silane Ligand

Robust and non-air-sensitive metal-free triazine-triazole heterogeneous organocatalysts were prepared. The synthetic procedure involved the co-condensation of a bridged tris silane precursor with tetraethyl orthosilicate (TEOS) in the presence of cetyltrimethylammonium bromide (CTAB). In addition, the silane precursor was anchored post-synthesis onto mesoporous silica nanoparticles and used to stabilize magnetic nanoparticles. The organocatalysts were characterized by X-ray diffraction (XRD), X-ray fluorescence (XRF), N2 adsorption-desorption, transmission electron microscopy (TEM), solid-state nuclear magnetic resonance spectroscopy (CP-MAS-NMR), Fourier-transform infrared spectroscopy (FT-IR), and UV/Vis diffuse reflectance spectroscopy (DRUV/Vis). All materials, recoverable and recyclable, possess good catalytic activity in Knoevenagel condensation and in the one-pot three-component reaction for the synthesis of 2-amino-chromene derivatives under mild conditions.

Synthesis and characterization of novel 1,2,3-triazole-linked theophylline and coumarin s-triazines

A series of novel s-triazine-1,2,3-triazole-theophylline and s-triazine-1,2,3-triazole-coumarin generation-0 dendrimers has been synthesized and characterized by FT-IR, 1H and 13C NMR, and mass-spectral methods. Some selected compounds have been evaluated for antibacterial and antifungal activity against a variety of strains and for anti-cancer activity against 60 human cancer cell lines.

HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD

To provide: a hydroxy group protecting agent which is stable and easy to use, does not have carcinogenicity, a tearing property or the like, and is inexpensive; and a hydroxy group protection method which enables the protection of a hydroxy group under acidic conditions. [Solution] A hydroxy group protecting agent in which at least one protecting group is bound to a nitrogen-containing electron-withdrawing heterocyclic ring through any one of an oxygen atom, a sulfur atom and a nitrogen atom. The heterocyclic ring is a triazine ring or the like, and the protecting group is a benzyl group or the like. Specifically, the hydroxy group protecting agent is 2,4,6-tribenzyloxy-1,3,5-triazine, 2,4,6-tris(4-methoxybenzyloxy)-1,3,5-triazine or the like. In addition, 2,4,6-tris(t-butoxy)-1,3,5-triazine or the like can also be used. For protecting a hydroxy group, a compound of interest which has a hydroxy group is reacted with the hydroxy group protecting agent under acidic conditions.

Synthesis and micellar mimic properties of bile acid trimers

Two fan-shaped bile acid trimers have been synthesized via Cu I-catalyzed azide-alkyne cycloaddition (CuAAC) 'click chemistry', and their extraction experiments of cresol red sodium (CR) and pyrene were investigated in the polar and non-polar solvents, respectively. The transmission electron microscopy (TEM) results showed that the homogenous hollow capsules formed with the diameter size range of 40-70 nm in a solution of water and acetone. Thus the amphiphilicity of fan-shaped bile acid trimers might be used as the promising candidate in biological and drug delivery applications.

Synthesis of fan-shaped C3 molecule with three glycyrrhetinic acid units and self-assembly properties

A novel fan-shaped C3 molecule with three glycyrrhetinic acid units was synthesized via "click chemistry" in high yield and the self-assembly characteristics were studied in different mixed solvents.

Simpler and more efficient strategy to stabilize the chromophore orientation in electro-optic polymers with copper-free thermal Huisgen reaction

A new strategy is proposed to stabilize the electro-optic (EO) activity of second-order materials using copper-free thermal Huisgen 1,3-dipolar cross-linking reaction. It consists in freezing the chromophores orientation after the poling process by a cross-linking reaction based on the 1,3-dipolar cycloaddition between an azide and an alkyne. To reach this goal, the synthesis of new methacrylate type polymers bearing a derivative of Disperse Red 1 chromophore was performed. The polymeric structure is bearing a cross-linkable function on its backbone and the complementary reactive function is brought by a small molecule called "doping agent" (DA), containing several complementary cross-linking groups, evenly distributed in the polymer film. Materials have been prepared and exhibit large second-order nonlinear optical coefficients (d33) up to 60 pm/V at the fundamental wavelength of 1064 nm. Moreover, the thermal stability of the orientation of the chromophores could reach 150 °C upon cross-linking with such materials, which is higher than previously described cross-linkable EO polymers based on this reaction. Furthermore, this new strategy widens the possibilities offered by copper-free thermal Huisgen 1,3-dipolar cycloaddition as cross-linking reaction for EO polymers.

ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE

The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs). The invention also relates to processes for the preparation of the conjugates. Such conjugates are useful in the prophylaxis and/or treatment of disease conditions and in particular chronic disease conditions such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites.