159152-07-5

Upstream product

• 25145-43-1 2-phenylpropionyl chloride 
• 1484-85-1 3,4-methylenedioxyphenylethylamine 

Downstream Products

• 159152-09-7 N-ethoxycarbonyl-1-(α-methylbenzylidene)-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline 
• 159152-08-6 1-(α-methylbenzyl)-6,7-methylenedioxy-3,4-dihydroisoquinoline 

Relevant academic research and scientific papers

Synthesis of 7-substituted dehydronoraporphines, with some biogenetic considerations

N-protected 7-methyl-6a,7-dehydronoraporphines were synthesized by the intermolecular benzyne cycloaddition approach. During basic hydrolysis of the N-protecting group, oxidation of these compounds by oxygen led to guacoline and other 7-hydroxy-7-methyl-6,6a-dehydronoraporphines in what may be a biomimetic process.