159171-18-3

Upstream product

• 98718-44-6 (R)-4-<(E)-5-hydroxy-3-methylpent-3-en-1-ynyl>-3,5,5-trimethylcyclohex-3-enol 
• 70905-70-3 <1R,4S,5R-(E)>-4-(5-Acetoxy-3-methylpent-3-en-1-ynyl)-4-hydroxy-3,3,5-trimethylcyclohexyl acetate 
• 70905-69-0 2-trans-5-<(4'R)-4'-acetoxy-2',6',6'-trimethylcyclohex-1'-enyl>-3-methyl-2-penten-4-yn-1-yl acetate 
• 152125-31-0 (4R,6R)-2,2,6-Trimethyl-4-trimethylsilanyloxy-cyclohexanone 
• 70905-68-9 (1S,4R,6R)-1-<(E)-5-hydroxy-3-methylpent-3-en-1-ynyl>-2,2,6-trimethylcyclohexane-1,4-diol 
• 20548-02-1 (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexan-1-one 

Downstream Products

• 162302-59-2 (2E,4E,6E,8E,10E)-13-((R)-4-Hydroxy-2,6,6-trimethyl-cyclohex-1-enyl)-2,7,11-trimethyl-trideca-2,4,6,8,10-pentaen-12-ynal 
• 190849-79-7 (all-E)-(3R)-3-Hydroxy-7,8-didehydro-8'-apo-β-caroten-8'-al 
• 31063-73-7 (all-E)-(3R,3'R)-diatoxanthin 

Relevant academic research and scientific papers

Total synthesis of acetylenic carotenoids-1. Synthesis of optically active 2-E-((4R)-4-hydroxy-2,6,6-trimethylcyclohex-1-enyl)-3-methyl-2 -penten-4-yn- 1-al, a C15-synthon

The title compound was synthesised in the optically active form in seven steps from (4R,6R)-actinol in 34% overall yield. The relative configuration within the C15-key intermediate acet-ylenic triol, 2-E-5-((1S,4R,6R)-1,4- dihydroxy-2,2,6-trime

Carotenoids and related polyenes. Part 3. First total synthesis of fucoxanthin and halocynthiaxanthin using oxo-metallic catalyst

The first total synthesis of optically active fucoxanthin 1 and halocynthiaxanthin 2 had been accomplished via the 8-oxo compound 5, efficiently prepared by rearrangement of the α-acetylenic alcohol 10 using oxo-metallic catalyst and subsequent iodine-catalysed double-bond shift.