159184-68-6Relevant articles and documents
Hypervalent iodine oxidation of phenol derivatives using a catalytic amount of 4-iodophenoxyacetic acid and Oxone as a co-oxidant
Yakura, Takayuki,Omoto, Masanori,Yamauchi,Tian, Yuan,Ozono, Ayaka
experimental part, p. 5833 - 5840 (2010/09/11)
Reaction of p-substituted phenols 2 with a catalytic amount of 4-iodophenoxyacetic acid (1) and Oxone as a co-oxidant in tetrahydrofuran (THF) or 1,4-dioxane-water gave the corresponding p-quinols 3 in excellent yields. Reaction of p-dialkoxyarenes 4 in 2,2,2-trifluoroethanol- water gave the corresponding p-quinones 5 in excellent yield without purification. These reactions provide efficient and practical methods for the preparation of p-quinols and p-quinones from p-substituted phenols and p-dialkoxyarenes, respectively. This quinone synthesis was applied to synthesis of blattellaquinone (13), the sex pheromone of the German cockroach Blattella germanica.
