124909-80-4

Basic information

• Product Name: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one
• Synonyms: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one
• CAS NO: 124909-80-4
• Molecular Weight: 554.596
• Mol File: 124909-80-4.mol

Chemical Properties

• CAS DataBase Reference: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one(124909-80-4)
• EPA Substance Registry System: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one(124909-80-4)

Safety Data

• Hazardous Substances Data: 124909-80-4(Hazardous Substances Data)

Upstream product

• 52378-73-1 2-(3,4-bis-benzyloxy-phenyl)-3-hydroxy-5,6,7-trimethoxy-chromen-4-one 
• 77-78-1 dimethyl sulfate 
• 1592-48-9 3,4-bis-benzyloxy-benzoic acid-anhydride 
• 14639-73-7 1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone 

Downstream Products

• 124909-95-1 Toluene-4-sulfonic acid 2-(3,4-bis-benzyloxy-phenyl)-3,6,7-trimethoxy-4-oxo-4H-chromen-5-yl ester 
• 124910-06-1 2-(3,4-Bis-benzyloxy-phenyl)-3,5-dihydroxy-6,7-dimethoxy-chromen-4-one 
• 124910-02-7 3',4'-bis(benzyloxy)-3-hydroxy-6,7-dimethoxy-5-(tosyloxy)flavone 
• 29536-45-6 3,3',4',5-Tetraacetoxy-6,7-dimethoxyflavon 
• 29536-44-5 3′-dimethoxy-5,6,4′-trihydroxyflavon 
• 24160-94-9 2-(3,4-Bis-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one 

Relevant articles and documents

Direct synthesis of chrysosplenol D

An aldol condensation and an Algar-Flynn-Oyamada oxidative cyclization were key steps in the direct synthesis of chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.

STUDIES OF THE SELECTIVE O-ALKYLATION AND DEALKYLATION OF FLAVONOIDS. XII. A NEW, CONVENIENT METHOD FOR SYNTHESIZING 3,5-DIHYDROXY-6,7-DIMETHOXYFLAVONES FROM 3,5,6,7-TETRAMETHOXYFLAVONES

The 5-methoxy group on 3,5,6,7-tetramethoxyflavones and the 3-methoxy group on 3,6,7-trimethoxy-5-tosyloxy-flavones were selectively cleaved with anhydrous aluminum bromide in acetonitrile under controlled conditions without the cleavage of benzyloxy groups on the B ring.By the application of these reactions, seven 3,5-dihydroxy-6,7-dimethoxyflavones were easily synthesized from the corresponding 3,5,6,7-tetramethoxyflavones which were synthesized from 3,6-dihydroxy-2,4ω-trimethoxycetophenone by means of the Allan-Robinson reaction followed by methylation.Keywords: Allan-Robinson reaction ; selective demethylation; 3,5,6,7-tetramethoxyflavone; 5-hydroxy-3,6,7-trimethoxyflavone; 6-hydroxy-3,5,7-trimethoxyflavone; 5-tosyloxyflavone; 5,6-dihydroxy-3,7-dimethoxyflavone; 3,5-dihydroxy-6,7-dimethoxyflavone, 3,5-diacetoxy-6,7-dimethoxyflavone