159262-92-7

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 159262-93-8 10-deacetylbaccatin III-13-O-[(4S,5R)-4-phenyl-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidine-5-carboxylate] 
• 143527-76-8 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-9-oxo-7β,10β-bis[(2,2,2-tri-chloroethoxy)carbonyloxy]-11-taxen-13α-yl (4S,5R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylate 
• 143615-03-6 (4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid 
• 95603-44-4 7,10-di-(2,2,2-trichloroethyloxycarbonyl)-10-deacetylbaccatin III 

Downstream Products

• 159262-91-6 C₄₆H₅₅NO₁₃ 
• 158811-30-4 10-O-deacetyl larotaxel 
• 159262-90-5 C₃₈H₄₃NO₁₁ 
• 162552-56-9 C₄₆H₅₆INO₁₃ 

Relevant academic research and scientific papers

Improved access to 19-nor-7β, 8β-methylene-taxoids and formation of a 7-membered C-ring analog of doxetaxel by electrochemistry

A new route to semisynthetic 19-nor-7β, 8β-methylene taxoids, such as compound 8, from the 7-O-trifluoromethanesulfonyl derivative 6 is reported. Evidence for a dissociation of the triflate to form a carbocation at C-7 under the reaction conditions is pre

Preparation of 7-Modified docetaxel analogs using electrochemistry

The electrochemical reduction of 7α -iodo docetaxel at E- 1.3V vs. SCE in methanol in the presence of lithium chloride and hydrochloric acid leads predominantiy to 7-deoxy-ocetaxel 9. When the electroreduction is conducted at E-1.7V vs. SCE in the presenc