159262-91-6Relevant academic research and scientific papers
Improved access to 19-nor-7β, 8β-methylene-taxoids and formation of a 7-membered C-ring analog of doxetaxel by electrochemistry
Bouchard, Herve,Pulicani, Jean-Pierre,Vuilhorgne, Marc,Bourzat, Jean-Dominique,Commercon, Alain
, p. 9713 - 9716 (2007/10/02)
A new route to semisynthetic 19-nor-7β, 8β-methylene taxoids, such as compound 8, from the 7-O-trifluoromethanesulfonyl derivative 6 is reported. Evidence for a dissociation of the triflate to form a carbocation at C-7 under the reaction conditions is pre
