159277-48-2Relevant academic research and scientific papers
NOVEL NUCLEOSIDE ANALOGS WITH POLYCYCLIC AROMATIC GROUPS ATTACHED, METHODS OF SYNTHESIS AND USES THEREFOR
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Page 11, (2010/02/08)
The present invention provides fluorescent nucleosides carrying polycyclic aromatic hydrocarbons such as anthracene, phenanthrene, pyrene, stilbene, tetracene or pentacene. The subject nucleosides may be synthesized using a C-glycosidic bond formation met
Naphthalene, phenanthrene, and pyrene as DNA base analogues: Synthesis, structure, and fluorescence in DNA
Ren, Rex X.-F.,Chaudhuri, Narayan C.,Paris, Pamela L.,Rumney IV, Squire,Kool, Eric T.
, p. 7671 - 7678 (2007/10/03)
We describe the synthesis, structures, and DNA incorporation of deoxyribonucleosides carrying polycyclic aromatic hydrocarbons as the DNA 'base' analogue. The new polycyclic compounds are 1-naphthyl, 2-naphthyl, 9-phenanthrenyl, and 1-pyrenyl deoxynucleos
Stabile DNA-Schleifen durch Einbau unpolarer und keine Wasserstoffbruecken bildener Nucleosid-Isostere
Ren, Xiao-Feng,Schweitzer, Barbara A.,Sheils, Charles J.,Kool, Eric T.
, p. 834 - 837 (2007/10/03)
Keywords: Basenstapelung; DNA; Nucleoside; Tripelhelix; Wasserstoffbruecken
Aromatic nonpolar nucleosides as hydrophobic isosteres of pyrimidine and purine nucleosides
Schweitzer,Kool
, p. 7238 - 7242 (2007/10/02)
Described are the design, synthesis, and structures of three nonpolar nucleoside isosteres to be used as probes of noncovalent bonding in DNA and as isosteric replacements for the natural nucleosides in designed nucleic acid structures. Reaction of substi
