159277-49-3

Upstream product

• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 3601-89-6 Hoffer's chlorosugar 
• 5469-19-2 1-bromo-2,4,5-trimethylbenzene 
• 164576-88-9 C₃₀H₃₂O₅ 

Downstream Products

• 272460-75-0 C₁₄H₂₃O₁₂P₃ 
• 162517-33-1 1',2'-dideoxy-5'-O-(4,4'-dimethoxytrityl)-1'-(1,2,4-trimethylphenyl)-β-D-ribofuranose 
• 159277-45-9 1',2'-Dideoxy-1'-(1,2,4-trimethylphenyl)-β-D-ribofuranose 

Relevant academic research and scientific papers

NOVEL NUCLEOSIDE ANALOGS WITH POLYCYCLIC AROMATIC GROUPS ATTACHED, METHODS OF SYNTHESIS AND USES THEREFOR

The present invention provides fluorescent nucleosides carrying polycyclic aromatic hydrocarbons such as anthracene, phenanthrene, pyrene, stilbene, tetracene or pentacene. The subject nucleosides may be synthesized using a C-glycosidic bond formation met

Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane

Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.

Efforts toward the expansion of the genetic alphabet: Information storage and replication with unnatural hydrophobic base pairs

The faithful recognition of the interstrand hydrogen bonds between complementary nucleobases forms the foundation of the genetic code. The ability to replicate DNA containing a stable third base pair would allow for an expansion of the information content

Naphthalene, phenanthrene, and pyrene as DNA base analogues: Synthesis, structure, and fluorescence in DNA

We describe the synthesis, structures, and DNA incorporation of deoxyribonucleosides carrying polycyclic aromatic hydrocarbons as the DNA 'base' analogue. The new polycyclic compounds are 1-naphthyl, 2-naphthyl, 9-phenanthrenyl, and 1-pyrenyl deoxynucleos

Stabile DNA-Schleifen durch Einbau unpolarer und keine Wasserstoffbruecken bildener Nucleosid-Isostere

Keywords: Basenstapelung; DNA; Nucleoside; Tripelhelix; Wasserstoffbruecken

An efficient method for the synthesis of aromatic C-nucleosides

Reaction of diarylcadmium or diarylzinc reagents with 1,2-dideoxy-3,5-di-O-p-toluoyl-1-chloro-α-D-ribofuranose affords 3,5-di-O-protected aromatic C-nucleosides in good yields.