1592771-91-9Relevant academic research and scientific papers
Stereoinversion of a tertiary alcohol on a THP ring: A recovery route to an intermediate for gymnocin-A
Sakai, Takeo,Aoyama, Kayo,Oshima, Rie,Furukawa, Kyoko,Mori, Yuji
, p. 523 - 540 (2019/07/31)
The stereoinversion of a tertiary alcohol on a tetrahydropyran ring was achieved through a five-step sequence including regioselective dehydration, diastereoselective epoxidation and reduction. This approach offers a recovery route from the diastereomer to the desired tertiary alcohol as part of the synthesis of gymnocin-A.
Synthesis of the KLMN fragment of gymnocin-A using oxiranyl anion convergent methodology
Sakai, Takeo,Asano, Haruka,Furukawa, Kyoko,Oshima, Rie,Mori, Yuji
supporting information, p. 2268 - 2271 (2014/05/06)
Synthesis of the KLMN fragment of gymnocin-A has been achieved by a [X + 2 + Y]-type convergent strategy involving the coupling of a K-ring triflate and an N-ring epoxy sulfone. Fusions of the L ring and the M ring were carried out by intramolecular Ssub
