159290-48-9

Basic information

• Product Name: 2-[3-(4-carboxyphenylsulfonylamino)-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide
• Synonyms: 2-[3-(4-carboxyphenylsulfonylamino)-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide
• CAS NO: 159290-48-9
• Molecular Weight: 579.554
• Mol File: 159290-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[3-(4-carboxyphenylsulfonylamino)-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(4-carboxyphenylsulfonylamino)-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide(159290-48-9)
• EPA Substance Registry System: 2-[3-(4-carboxyphenylsulfonylamino)-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide(159290-48-9)

Safety Data

• Hazardous Substances Data: 159290-48-9(Hazardous Substances Data)

Upstream product

• 10130-89-9 p-carboxyphenylsulfonyl chloride 
• 147267-64-9 2-(3-amino-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide 

Downstream Products

• 7647-01-0 hydrogenchloride 

Relevant articles and documents

Nonpeptidic inhibitors of human leukocyte elastase. 6. Design of a potent, intratracheally active, pyridone-based trifluoromethyl ketone

Further modification of the 3-amino substituent in a trifluoromethyl ketone-based series of 3-amino-6-phenylpyridin-2-ones that had been optimized for oral activity led to analogs that were potent intratracheal inhibitors in a model of HLE-induced lung da