159298-77-8

Upstream product

• 110-91-8 morpholine 
• 949-01-9 1-(morpholin-4-yl)-2-phenylethanethione 
• 122-51-0 orthoformic acid triethyl ester 
• 22630-09-7 trimorpholylmethane 
• 98-86-2 acetophenone 

Downstream Products

• 98236-46-5 ((E)-3-Morpholin-4-yl-2-phenyl-3-thioxo-propenylamino)-acetic acid methyl ester 
• 952613-94-4 2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3-phenyl-3H-quinazolin-4-one 

Relevant academic research and scientific papers

THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS

Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.

Design, synthesis, and pharmacological evaluation of some 2-[4-morpholino]-3-aryl-5-substituted thiophenes as novel anti-inflammatory agents: Generation of a novel anti-inflammatory pharmacophore

We report the synthesis and pharmacological evaluation of some novel 2-morpholino-3-aryl-5-substituted thiophenes, as possible anti-inflammatory leads. The studies culminate in the generation of a novel pharmacophore, which will enable the designing of be

Efficient synthesis of 3-aminothioacrylamides by iminoformylation of thioacetamides

Heating substituted thioacetamides 1 with either trismorpholinomethane or with a mixture of triethyl orthoformate and a secondary amine gives high yields of synthetically versatile 3-aminothioacrylamides 4.