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Relevant academic research and scientific papers

RETRACTED ARTICLE: Pt NPs@GO as a highly efficient and reusable catalyst for one-pot synthesis of acridinedione derivatives

Graphene oxide decorated with platinum nanoparticles (Pt NPs@GO) has been used for the first time as a highly stable, exceptionally reusable, isolable, bottleable, long-lived and highly efficient catalyst for the synthesis of acridinedione derivatives from dimedone, aromatic aldehydes and various amines with great catalytic performance. All the acridinedione compounds were synthesized in DMF in a single process through two successive reactions (aldol condensation and Michael addition) in the presence of highly efficient Pt NPs@GO. The synthesized catalyst was characterized by transmission electron microscopy (TEM), high resolution electron microscopy (HRTEM), X-ray diffraction (XRD), atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). All products obtained using Pt NPs@GO were characterized by FT-IR, 1H-NMR, 13C-NMR and HRMS techniques.

Synthesis of novel acridine-sulfonamide hybrid compounds as acetylcholinesterase inhibitor for the treatment of alzheimer’s disease

In this study we report that amino acridine intermediates 7 and 8 were obtained from the reduction of nitro acridine derivatives 5 and 6 that were synthesized via the condensation of dimedone, p-nitrobenzaldehyde with various amine derivatives, respective

Carbon-based nanocatalyst:?An efficient and recyclable heterogeneous catalyst for one-pot synthesis of gem-bisamides, hexahydroacridine-1,8-diones and 1,8-dioxo-octahydroxanthenes

Abstract: In this abstract, we discuss the progress related to sulfonated carbon-based materials in various acid-catalyzed organic transformations which are then further utilized in medicinal field, laboratories and industries. A simple and novel methodol

Graphene oxide as highly effective and readily recyclable catalyst using for the one-pot synthesis of 1,8-dioxoacridine derivatives

Graphene oxide as a highly stable, reusable, isolable, and efficient catalyst has been used for the first time for the synthesis of acridinedione derivatives from dimedone, aromatic aldehydes and various amines with great catalytic performance. One pot synthesis of acridinedione compounds were performed using highly efficient graphene oxide.

One-Pot, Facile, Highly Efficient, and Green Synthesis of Acridinedione Derivatives Using Vitamin B 1

An efficient methodology for the synthesis of acridinedione derivatives 4a-o has been achieved by one-pot, multicomponent condensation of dimedone 1, various amines 2a-d, and substitute aromatic aldehydes 3a-k, in the presence of the easily available, inexpensive, and nontoxic catalyst vitamin B1(VB1) as a versatile biodegradable. Synthesis of acridine-type compounds was performed in good yields in water as green solvent. Its high-yield efficiency; clean, ecofriendly, simple workup procedure; and easy purification are regarded as the main advantages of this method besides its green solvent. The synthesized compounds are characterized using spectroscopic analyses (FTIR, 1H NMR, 13C NMR, and high-resolution mass spectrometry) techniques.

A green procedure for the synthesis of 1,8-dioxodecahydroacridine derivatives under microwave irradiation in aqueous media without catalyst

(Chemical Equation Presented) A green procedure for the synthesis of 1,8-dioxo-decahydroacridine derivatives is developed under microwave irradiation without catalyst in water. This method provides several advantages such as excellent yields (86-96%), simple workup procedure, and environment friendliness.