159333-27-4Relevant academic research and scientific papers
Bioreductive Markers for Hypoxic Cells: 2-Nitroimidazoles with Biotinylated 1-Substituents
Hodgkiss, Richard J.,Parrick, John,Porssa, Manuchehr,Stratford, Michael R. L.
, p. 4352 - 4356 (1994)
The interference by oxygen with the bioreductive metabolism and binding within cells of 2-nitroimidazoles has been used to identify hypoxic cells.Three novel compounds were synthesized with a 1-substituent containing a biotin moiety.Bound adducts of these
