122224-39-9Relevant academic research and scientific papers
Improved synthesis of biotinol-5′-AMP: Implications for antibacterial discovery
Tieu, William,Polyak, Steven W.,Paparella, Ashleigh S.,Yap, Min Y.,Soares Da Costa, Tatiana P.,Ng, Belinda,Wang, Geqing,Lumb, Richard,Bell, Jan M.,Turnidge, John D.,Wilce, Matthew C. J.,Booker, Grant W.,Abell, Andrew D.
, p. 216 - 220 (2015/03/04)
An improved synthesis of biotinol-5′-AMP, an acyl-AMP mimic of the natural reaction intermediate of biotin protein ligase (BPL), is reported. This compound was shown to be a pan inhibitor of BPLs from a series of clinically important bacteria, particularl
