1593585-84-2

Basic information

• Product Name: (-)-(3R,5S)-methyl 2-benzyl-5-formyl-5-methyl-3-propylisoxazolidine-3-carboxylate
• CAS NO: 1593585-84-2
• Molecular Weight: 305.374
• Mol File: 1593585-84-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(3R,5S)-methyl 2-benzyl-5-formyl-5-methyl-3-propylisoxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3R,5S)-methyl 2-benzyl-5-formyl-5-methyl-3-propylisoxazolidine-3-carboxylate(1593585-84-2)
• EPA Substance Registry System: (-)-(3R,5S)-methyl 2-benzyl-5-formyl-5-methyl-3-propylisoxazolidine-3-carboxylate(1593585-84-2)

Safety Data

• Hazardous Substances Data: 1593585-84-2(Hazardous Substances Data)

Upstream product

• 78-85-3 2-methylpropenal 
• 1593585-66-0 (E)-N-(1-methoxy-1-oxopentan-2-ylidene)-1-phenylmethanamine oxide 
• 6376-59-6 Methyl-2-oxopentanoate 
• 622-30-0 N-benzyl hydroxylalmine 

Relevant articles and documents

Enantioselective ruthenium-catalyzed 1,3-dipolar cycloadditions between C -carboalkoxy ketonitrones and methacrolein: Solvent effect on reaction selectivity and its rational

A catalytic 1,3-dipolar cycloaddition between carboalkoxy ketonitrones and methacrolein under the effect of chiral ruthenium Lewis acid (R,R-1) was developed with high regio-, diastereo-, and enantiocontrol. The diastereochemical outcome of the cycloaddition reaction is marked by a significant solvent effect, and a divergent endo or exo control can be tuned by an appropriate choice of both the solvent and the N- and O-substituents of the ketonitrone. A rationale of the solvent effect, based on the computational study of the interactions between the methacrolein-Ru complex and its counteranion (SbF6-), is proposed to explain the selectivities obtained.