15937-10-7

Basic information

• Product Name: 1-Acetyl-5,6-dimethoxyindoline
• Synonyms: 1-Acetyl-5,6-dimethoxyindoline;1-(5,6-DiMethoxyindolin-1-yl)ethanone
• CAS NO: 15937-10-7
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.2524
• Mol File: 15937-10-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 452.528 °C at 760 mmHg
• Flash Point: 227.481 °C
• Appearance: /
• Density: 1.172 g/cm³
• CAS DataBase Reference: 1-Acetyl-5,6-dimethoxyindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Acetyl-5,6-dimethoxyindoline(15937-10-7)
• EPA Substance Registry System: 1-Acetyl-5,6-dimethoxyindoline(15937-10-7)

Safety Data

• Hazardous Substances Data: 15937-10-7(Hazardous Substances Data)

Usage

General Description

1-Acetyl-5,6-dimethoxyindoline is a chemical compound with the molecular formula C12H13NO3. It is a derivative of indoline, which is a heterocyclic aromatic organic compound. This particular derivative consists of an acetyl group and two methoxy groups attached to the indoline ring. It has potential applications in the field of organic synthesis and pharmaceutical research due to its unique chemical structure. Additionally, it may exhibit certain biological activities or pharmacological properties, making it of interest for further study. Its specific properties and potential uses may make it valuable for research and development in various industries.

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 66384-45-0 N-acetyl-2-iodo-4,5-dimethoxy-β-phenethylamine 
• 6275-29-2 N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide 
• 74064-26-9 N-[2-(2-bromo-4,5-dimethoxyphenyl)ethyl]acetamide 

Downstream Products

• 29539-03-5 5,6-dihydroxy-indoline 
• 138937-28-7 5,6-dihydroxyindoline hydrobromide 
• 14430-23-0 5,6-dimethoxyindole 

Relevant articles and documents

Preparation method of compound 5,6-dihydroxy indoline and halogen acid salts thereof

The invention relates to a preparation method of a compound 5,6-dihydroxy indoline and halogen acid salts thereof. Phenylethylamine SM-0 sold in the market is used as a raw material and firstly reactswith acyl chloride to obtain amide SM-1; amide SM-1 rea

Studies on the Syntheses of Heterocyclic Compounds. Part 865. A Novel Synthesis of Indole Derivatives by Intramolecular Nucleophilic Aromatic Substitution

Cyclisation of N-(2-bromo-4,5-dimethoxyphenethyl)acetamide (6) afforded 1-acetyl-2,3-dihydro-5,6-dimethoxy-1H-indole (13) by intramolecular nucleophilic aromatic substitution using sodium hydride and cuprous halide in dimethylformamide.The dihydroindoles (14), (15), and (16) were also synthesised from the corresponding amides (8) and (10) and the carbamate (12) in a similar manner.The dihydroindoles (13), (14), and (16) were converted into the indoles (20) and (21) in excellent yield by oxidation and subsequent alkaline hydrolysis.The 2-oxindoles (26) and (27) were also prepared under similar reaction condition from the phenylacetamide (24) and (25).