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Usage

Uses

Used in Organic Synthesis:
Bicyclo[3.1.0]hex-2-ene, 5-(1,5-dimethyl-4-hexenyl)-2-methylis employed as a key intermediate in organic synthesis for the production of a variety of chemical compounds. Its unique structure allows for versatile reactions and transformations, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Bicyclo[3.1.0]hex-2-ene, 5-(1,5-dimethyl-4-hexenyl)-2-methylis used as a building block for the development of novel drug candidates. Its unique structure and reactivity enable the creation of new molecules with potential therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Fragrance Industry:
Bicyclo[3.1.0]hex-2-ene, 5-(1,5-dimethyl-4-hexenyl)-2-methylis also utilized in the fragrance industry as a component in the creation of unique and complex scents. Its distinctive chemical structure contributes to the development of new fragrance compounds, enhancing the variety and quality of perfumes and other scented products.
Used in Industrial Applications:
Beyond its applications in organic synthesis, pharmaceuticals, and fragrances, Bicyclo[3.1.0]hex-2-ene, 5-(1,5-dimethyl-4-hexenyl)-2-methylis also employed in various industrial applications. Its unique properties and reactivity make it suitable for use in the development of new materials, coatings, and other industrial products, contributing to innovation and progress in these fields.

Upstream product

• 372-97-4 farnesyl pyrophosphate 
• 1309584-99-3 C₁₅H₂₁F₃O₃S 
• 75-16-1 methylmagnesium bromide 

Relevant academic research and scientific papers

Isotope sensitive branching and kinetic isotope effects to analyse multiproduct terpenoid synthases from Zea mays

Multiproduct terpene synthases TPS4-B73 and TPS5-Delprim from Zea mays exhibit isotopically sensitive branching in the formation of mono- and sesquiterpene volatiles. The impact of the kinetic isotope effects and the stabilization of the reactive intermediates by hyperconjugation along with the shift of products from alkenes to alcohols are discussed.

Absolute configuration of 7-epi-sesquithujene

7-epi-Sesquithujene (1) is a bicyclic sesquiterpene isolated from phoebe oil, an essential oil of the Brazilian walnut tree, Phoebe porosa. It is also produced by stressed ash trees and has been shown to elicit strong electrophysiological responses on emerald ash borer, Agrilus planipennis, antennae. In the course of the development of a synthetic 7-epi-sesquithujene lure for field testing against the emerald ash borer, we found that the absolute configuration of this compound had not been determined. We isolate >95% pure 7-epi-sesquithujene from phoebe oil via successive fractionation and conventional and argentation (HPLC) chromatographies. The specific optical rotation of this compound matched that of a synthetic product of known configuration. We also synthesized two other stereoisomers of sesquithujene and developed a chiral GC method to separate all four. Based on the specific rotation, stereoselective syntheses, and chiral GC analyses, 7-epi-sesquithujene present in phoebe oil and white ash was found to have the 2S,6S,7R absolute configuration. This article not subject to U.S. Copyright. Published 2011 by the American Chemical Society.