1594439-49-2

Upstream product

• 117009-97-9 benzyl 1,4-diazepane-1-carboxylate 
• 92-92-2 biphenyl-4-carboxylic acid 

Downstream Products

• 1594439-40-3 2-(10-(4-(biphenylcarbonyl)-1,4-diazepan-1-yl)decyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione 
• 1594439-41-4 2-(10-(4-(biphenylcarbonyl)-1,4-diazepan-1-yl)decyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-42-5 2-(10-(4-(biphenylcarbonyl)-1,4-diazepan-1-yl)decyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-43-6 2-(10-(4-(biphenylcarbonyl)-1,4-diazepan-1-yl)decyl)-3-methylnaphthalene-1,4-dione 
• 815650-69-2 C₁₈H₂₀N₂O 

Relevant academic research and scientific papers

Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy

A series of novel bivalent mimetics of annonaceous acetogenins have been designed, synthesized, and evaluated. Among these, compound 7 bearing a homopiperazine ring in the middle region exhibited more potent growth inhibitory activity and higher selectivity against cancer cells over normal cells by comparison with AA005. This work indicates that modification of the middle piperazine ring is a useful optimizing tool for the simplified acetogenin mimetics.