1594966-46-7

Basic information

• Product Name: C₂₂H₁₈FNO₄
• Synonyms: C₂₂H₁₈FNO₄
• CAS NO: 1594966-46-7
• Molecular Weight: 379.388
• Mol File: 1594966-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₈FNO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₈FNO₄(1594966-46-7)
• EPA Substance Registry System: C₂₂H₁₈FNO₄(1594966-46-7)

Safety Data

• Hazardous Substances Data: 1594966-46-7(Hazardous Substances Data)

Upstream product

• 99532-53-3 1-(5-fluoro-1H-indol-3-yl)ethan-1-one 
• 1594966-07-0 4-[1-(3,5-dimethylbenzyl)-5-fluoro-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid 
• 399-52-0 5-fluoro-1H-indole 
• 1594965-29-3 3-acetyl-1-(3,5-dimethylbenzyl)-5-fluoro-1H-indole 
• 1594965-67-9 ethyl 4-[1-(3,5-dimethylbenzyl)-5-fluoro-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoate 

Relevant articles and documents

A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition

Therapeutic treatment of AIDS is recently characterized by a crescent effort towards the identification of multiple ligands able to target different steps of HIV-1 life cycle. Taking into consideration our previously obtained SAR information and combining some important chemical structural features we report herein the synthesis of novel benzyl-indole derivatives as anti-HIV agents. Through this work we identified new dual target small molecules able to inhibit both IN-LEDGF/p75 interaction and the IN strand-transfer step considered as two crucial phases of viral life cycle.